Korven
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- May 4, 2019
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I managed to narrow down severe electrical symptoms to vitamin D supplementation (at reasonable doses and with 30ng blood levels). repeated non-stop twitching all over my body & face, sudden involuntary foot movement, erratic heart rhythm changes with sharp electrical spike pains, & also waking up in adrenaline rushes. + the common recommendation of magnesium just took it up a notch made it worse.
It all settled once I stopped supplementation & levels came down in winter without sun. all came back once i re-tried the D3. and now it annoyingly comes back from summer sunlight after a couple weeks.
- idk for sure but the only angle I got for this so far is that it's some sort of hyper-response with calcium that doesn't show up in serum as hypercalcemia (severe soft tissue calcification can occur in people without showing up in blood work as over the range). considering my diet has been low in vitamin k and vitamin A for many years and very low in calcium (mainly from fortified grain since i stopped milk last decade, which i recently realized is ridiculous intake). so this is worth a shot (k1 + vit a + mk4 + calcium (unintitively) as more in diet reverses parathyroid hormone effects)
View: https://www.youtube.com/watch?v=9H7tbWVNrXQ
https://chrismasterjohnphd.com/blog/2009/04/07/tufts-university-confirms-that-vitamin
^ Vitamin D alone spikes up the levels of defective uncarboxylated MGP which can't bind calcium (wonder if its directly harmful too on top of not being effective?).
Ordinarily with enough Vitamin A and K1 this brings down the level of uncarboxylated MGP and carboxylates it, through increasing conversion of K1 -> k2 mk4 and increasing utilization of mk-4 to carboxylate the MGP elevated by vit d. then calcium is binding correctly instead of wrecking havoc in places it shouldn't be.
https://academic.oup.com/ckj/article/11/4/528/4616523
^ Interestingly there's a case report in a woman with an extreme form of soft tissue calcium deposit. she was cured by giving this protocol for months -
"Intravenous therapy was begun with 10 mg vitamin K and a multivitamin given at every dialysis session. The multivitamin contained retinol 3500 IU, cholecalciferol 5.5 μg, vitamin E 11.2 IU, vitamin C 125 mg, thiamine 3.51 mg, riboflavine 4.14 mg, pyridoxine 4.53 mg, cyanocobalamin 6 μg, folic acid 414 μg, dexpanthenoic acid 17.25 mg, d-biotin 69 μg, niacin 46 mg, glycocholic acid 140 mg and lecithin 112.5 mg. "
Currently trying:
- 700,000iu total Vit A spread out over a month or so - in people with low intakes a +10% response in serum is seen by 1 month from 70,000iu weekly Vitamin A supplementation and plasma retinol levels: a randomized trial among women - PubMed and as an example in an autism study in children where vit a deficiency is high a ~+50% correction in serum was needed to reach standard levels which came with 1 dose 200,000iu (maybe 3.5x - 4x bodyweight for an adult). another study in aids patients showed i think around +25% increase with 1 600,000iu dose by 3 months (doesnt seem safe like that though). [so far this has made me feel lightheaded / dizzy / weak for some reason - maybe the palmitate form might try another]
- k2 mk-4 1.5mg - Low-dose menaquinone-4 improves γ-carboxylation of osteocalcin in young males: a non-placebo-controlled dose–response study
- k1 1mg - 2mg A high phylloquinone intake is required to achieve maximal osteocalcin gamma-carboxylation - PubMed
- calcium 500mg every 4-6 hours morning afternoon evening to keep parathyroid hormone low https://www.researchgate.net/public...plementation_on_Parathyroid_Hormone_Secretion
(solgar k1 for a couple days initially increased anxiety a lot (maybe as low dose could be all the other ingredients x10 not sure) so i've switched suppliers to try a different source. maybe just the Vit A + mk-4 is enough as then dont need much k1 conversion to k2 but going by the case report i'll try all of them. worth a shot to see if it works for 1 or 2 months and good to have anyway)
Not sure how relevant this is to your situation and unique context, but I started developing calcified bumps on the back of my hands after several months of taking large doses of supplemental vitamin D (both orally and topically in navel), eating a lot of calcium-rich foods and hardly drinking any water. For several years before this I had also been taking "reasonable" doses of vitamin D ranging from 2000-5000 units per day. Now that you mention it I did experience muscle twitching/involuntary movements occasionally.
Since I stopped the supplemental vitamin D cold turkey around 2 years ago, started drinking 2-3 liters of water everyday, along with taking vitamin K2 and boron, the soft tissue calcium deposits (?) on my hands have gradually dissolved and are barely noticeable any longer. This was freaking me out because I could see the deeper arteries pulsating under the skin as the calcified deposits pushed them to the surface. Never ******* touching vitamin D again. Sun never had this effect on me.
Also I would be careful about trying to rectify the situation with vitamin A supplementation. See the Grant Genereux "Poison A" thread for retinol supplementation horror stories. In fact I think there is some evidence that hypervitaminosis A can lead to bone resorption and hypercalcemia. I would just focus on whole foods with retinol like dairy and eggs.