Douglas Ek
Member
- Joined
- Feb 8, 2017
- Messages
- 642
Dunno if theres a correlation but i know melanin is dependent on copper. The dopamine producing region substantia nigra in the basal ganglia of the brain (the area affected mostly in parkinsons disease) also containt neuromelanin cells that control the dopamine release (if it has melanin the in probably has copper). This area is also the most iron rich area of the brain. Studies have shown both cell death and symptoms of parkinson in people with to much iron in this area as people with lowered iron also show symptons restless legs and inhibited dopamine signaling. So iron seem essential to the dopaminergic function of the brain but to much is linked to cell death of the dopamine neurons. Copper has many ways to protect the body from iron excess. It helps keep iron out of depositing in the wrong places and transporting iron around the body to the right places through ceruloplasmin aswell protectin from oxidative stress caused by iron through the powerful SOD antioxidant system. Just another study proving the importance of copper regulation.
X-rays reveal the important role of copper in Parkinson’s disease
Another study also showed vitamin D protected these neurons aswell and that vitamin A was toxic Evaluation of the effects of vitamin A supplementation on adult rat substantia nigra and striatum redox and bioenergetic states: mitochondrial impair... - PubMed - NCBI
The rat doses was 1000-9000 IU vitamin-A. Dunno if they already converted that to human equiv but might be super high dosage
X-rays reveal the important role of copper in Parkinson’s disease
Another study also showed vitamin D protected these neurons aswell and that vitamin A was toxic Evaluation of the effects of vitamin A supplementation on adult rat substantia nigra and striatum redox and bioenergetic states: mitochondrial impair... - PubMed - NCBI
The rat doses was 1000-9000 IU vitamin-A. Dunno if they already converted that to human equiv but might be super high dosage
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