Candeias
Member
- Joined
- Apr 29, 2018
- Messages
- 220
I have to use high doses of Niacinamide to correct a problem, last time I was doing fine until I put too much stuff for my liver, I got up to 3 grams with no problems.
But what is essential to take to avoid problems of excess of undermethylation and high homocysteine? Does anyone have experiences with this?
As far as I know I don't have serious genetic/enzymatic problems.
Thanks
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Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives
But what is essential to take to avoid problems of excess of undermethylation and high homocysteine? Does anyone have experiences with this?
As far as I know I don't have serious genetic/enzymatic problems.
Thanks
___________________________________________
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives - Hypertension Research
Nicotinamide and catecholamines are both degraded by S-adenosylmethionine-dependent methylation. Whether excess nicotinamide affects the degradation of catecholamines is unknown. The aim of this study was to investigate the effect of nicotinamide on the methylation status of the body and...
www.nature.com