Zpol
Member
- Joined
- Apr 14, 2013
- Messages
- 929
- Age
- 45
Haidut's summarization of the article
Protective CO2 and aging
Is...
"methylation can be thought of as a direct measure of aging (or cancer potential) and reversing it is thought to be beneficial both for anti-aging and anti-cancer purposes. Baking soda, bag breathing, sugar (and efficient metabolism for its conversion to CO2), acetazolamide, niacinamide are all methods that are known to directly cause demethylation."
I have a gene variant called MTHFR SNP and am lacking methyl donors an so have severe nutritional deficiencies (despite eating high nutrient diet) and my liver is poor at phase I and phase II detoxification.
The article states... "...Restriction of methyl donors causes demethylation of DNA". And so it correlates (or results from? IDK) with biological youth and prevention of degenerative disease.
I am lacking methyl donors, so shouldn't I be feeling very youthful and healthy?!?
And how do I supplement to improve my health? I would theoretically need methyl forms of folate and B-12 but these are correlated with cancer (sorry I can't find my link for that, but I have a quote from Haidut "Possibly yes, but I think folic acid and B12 have other issues beyond just methylation. Both of them have been linked to cancer in adult and the recent studies seem to be more and more towards causal link. It is one of the reasons I don't have these two vitamins in Energin.")
Been looking at this every which way and cannot understand. Although, one thing I noticed is that when RP writes of demethylation he's referring to DNA, and my lacking methyl donors have to with FAD, which is an electron acceptor. (Sorry can't find my link to this either, I'm on my phone, I will edit to include when i get home).
Protective CO2 and aging
Is...
"methylation can be thought of as a direct measure of aging (or cancer potential) and reversing it is thought to be beneficial both for anti-aging and anti-cancer purposes. Baking soda, bag breathing, sugar (and efficient metabolism for its conversion to CO2), acetazolamide, niacinamide are all methods that are known to directly cause demethylation."
I have a gene variant called MTHFR SNP and am lacking methyl donors an so have severe nutritional deficiencies (despite eating high nutrient diet) and my liver is poor at phase I and phase II detoxification.
The article states... "...Restriction of methyl donors causes demethylation of DNA". And so it correlates (or results from? IDK) with biological youth and prevention of degenerative disease.
I am lacking methyl donors, so shouldn't I be feeling very youthful and healthy?!?
And how do I supplement to improve my health? I would theoretically need methyl forms of folate and B-12 but these are correlated with cancer (sorry I can't find my link for that, but I have a quote from Haidut "Possibly yes, but I think folic acid and B12 have other issues beyond just methylation. Both of them have been linked to cancer in adult and the recent studies seem to be more and more towards causal link. It is one of the reasons I don't have these two vitamins in Energin.")
Been looking at this every which way and cannot understand. Although, one thing I noticed is that when RP writes of demethylation he's referring to DNA, and my lacking methyl donors have to with FAD, which is an electron acceptor. (Sorry can't find my link to this either, I'm on my phone, I will edit to include when i get home).