Ahanu
Member
- Joined
- Sep 13, 2015
- Messages
- 432
Maybe the metabolic rate is not so important after all. Mathematician/biologist Lloyd Demetrius suggested that the most important factor involved in duration of life is not metabolic rate or oxidative stress, but metabolic stability.
"Evolutionary biologist Lloyd Demetrius believes that life-span potential is related to an organism’s ability to maintain stable levels of critical cellular metabolites, not to its metabolic rate. The traditional theory that longevity and rate of aging are determined by metabolic rate and the rate of production of free radicals has had broad appeal as an explanationfor why some animals live longer than others. But numerous exceptions to this rule (including the FIRKO mouse) have undermined the idea over time."
The Aging Enigma
Has anyono looked into the work Lloyd Demetrius ?
"Evolutionary biologist Lloyd Demetrius believes that life-span potential is related to an organism’s ability to maintain stable levels of critical cellular metabolites, not to its metabolic rate. The traditional theory that longevity and rate of aging are determined by metabolic rate and the rate of production of free radicals has had broad appeal as an explanationfor why some animals live longer than others. But numerous exceptions to this rule (including the FIRKO mouse) have undermined the idea over time."
The Aging Enigma
Has anyono looked into the work Lloyd Demetrius ?