Such_Saturation
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- Nov 26, 2013
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Wouldn't 600mg make your eyes blue?
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Embrace the Spice...Such_Saturation said:https://raypeatforum.com/forums/posts/97905/ Wouldn't 600mg make your eyes blue?
I am considering this too.sunmountain said:https://raypeatforum.com/forums/posts/97931/ If nothing else works for sibo, who knows I might want to try MB for it at some point.
haidut said:https://raypeatforum.com/forums/posts/97870/sunmountain said:https://raypeatforum.com/forums/posts/97777/ Hi Haidut,
I recently began to have thyroid working for me at effective doses, and am continuing to slowly increase it (t3 and t4). My methane sibo and its bloat is still there, though I think transit is slowly improving especially with t3.
From your post above, it seems you prefer MB over thyroid. May I ask why? Are there downsides to thyroid that MB does not have, or benefits to MB that thyroid cannot provide?
I am thrilled that thyroid is finally working for me. I'm still fiddling with the dosage, and expect it will take a few more weeks to get it right. I'm wondering if MB has a role if thyroid is working -- apart from the issue of using it for sibo which you recommended and I'm still considering, as nothing else has worked for it so far. I do also have a fatty liver, and don't know if that can be addressed by thyroid alone, or better in conjunction with MB once I settle on a dose for thyroid.
Thank you
If thyroid is working for you I would not mess with it. I am one of the people for whom thyroid was always hit or miss and I always got better response with thyroid "surrogates" so to speak, including caffeine. Ray said that MB works like thyroid in sub-milligram doses and I prefer it b/c thyroid is a hormone and it leads to the suppression of the natural production of thyroid form your own gland. In some cases this is the only option that works, but in my case I get better results from MB and caffeine and I also prefer to not inhibit natural thyroid synthesis. This is the reason I do not like supplementing with steroids at the end of the pathways since they all have negative feedback mechanisms and suppress endogenous production. Pregnenolone, progesterone, and DHEA do not have such drawbacks AFAIK.
So, bottom line - caffeine and MB work better for me than thyroid in terms of temperature, pulse and energy. And caffeine is hugely dopaminergic for me, which is something thyroid does not do.
Everybody is different, so if thyroid works for you I'd stick with it.
RPDiciple said:https://raypeatforum.com/forums/posts/97901/ Haidut: how much sugar or meal of sugar/protein do you need to have for each 600mg dose to not get a stress reaction'?
Such_Saturation said:https://raypeatforum.com/forums/posts/97905/ Wouldn't 600mg make your eyes blue?
Makrosky said:https://raypeatforum.com/forums/posts/97903/haidut said:Nick Ireland said:https://raypeatforum.com/forums/posts/91339/ I'm ordering from Haidut shortly, though. None of his customers are fish, that I know of
Lol, that's correct. The MB we use for Oxidal is USP-quality and is approved for human use.
Btw, great update Nick! I am glad MB is helping so much. The only thing I would add to that regimen is a little caffeine (as in Oxidal). Start with a lower dose caffeine (100mg) first and increase as needed.
WARNING: That "protocol" will cause uncoupling and will make you sweat buckets but it will also greatly add to that feeling of youth you describe and I have experienced myself. I personally get it from the 600mg caffeine doses I take a few times a day. Took me about a month to work up to that dose (1,500mg caffeine daily) but now I understand why all the animal studies use similar dose and why Peat himself takes more than 1,000mg caffeine daily. It makes you hot (literally) and young again and removes the need for any type of thyroid supplementation. I am even afraid to add aspirin now since caffeine by itself raises my temperatures so much...
Hey haidut, could you please elaborate a little bit more on the relation about uncoupling of the mithocondria and sweating a lot ?
Is sweating good in a context of increasing metabolism ? Does it stop once metabolism is restored ?
Thanks in advance man.
cantstoppeating said:https://raypeatforum.com/forums/posts/97973/haidut said:https://raypeatforum.com/forums/posts/97870/sunmountain said:https://raypeatforum.com/forums/posts/97777/ Hi Haidut,
I recently began to have thyroid working for me at effective doses, and am continuing to slowly increase it (t3 and t4). My methane sibo and its bloat is still there, though I think transit is slowly improving especially with t3.
From your post above, it seems you prefer MB over thyroid. May I ask why? Are there downsides to thyroid that MB does not have, or benefits to MB that thyroid cannot provide?
I am thrilled that thyroid is finally working for me. I'm still fiddling with the dosage, and expect it will take a few more weeks to get it right. I'm wondering if MB has a role if thyroid is working -- apart from the issue of using it for sibo which you recommended and I'm still considering, as nothing else has worked for it so far. I do also have a fatty liver, and don't know if that can be addressed by thyroid alone, or better in conjunction with MB once I settle on a dose for thyroid.
Thank you
If thyroid is working for you I would not mess with it. I am one of the people for whom thyroid was always hit or miss and I always got better response with thyroid "surrogates" so to speak, including caffeine. Ray said that MB works like thyroid in sub-milligram doses and I prefer it b/c thyroid is a hormone and it leads to the suppression of the natural production of thyroid form your own gland. In some cases this is the only option that works, but in my case I get better results from MB and caffeine and I also prefer to not inhibit natural thyroid synthesis. This is the reason I do not like supplementing with steroids at the end of the pathways since they all have negative feedback mechanisms and suppress endogenous production. Pregnenolone, progesterone, and DHEA do not have such drawbacks AFAIK.
So, bottom line - caffeine and MB work better for me than thyroid in terms of temperature, pulse and energy. And caffeine is hugely dopaminergic for me, which is something thyroid does not do.
Everybody is different, so if thyroid works for you I'd stick with it.
I'm similar, I tried thyroid (cynoplus) but it didn't have the beneficial effects unless I was only taking T3 (cynomel) in hourly physiological doses but then that become too impractical. Instead a daily dose of 30mg pregnenolone does everything thyroid is purported to do: stable temps, warms hand and feet, pink-reddish skin tone (i.e. good blood flow).
Then I tried a drop of MB (oxidial) in water and within 10 minutes experienced faster heart beat, warmer hands and feet. And now I'm coupling it with 1g of aspirin twice daily to increase the uncoupling effect. Good things are happening.
About caffeine, this is what I don't understand. You've said that handling caffeine is a good indication of liver status yet the mainstream explanation is that handling caffeine is the result of adenosine receptors up-regulating to the dose of caffeine so that over time one needs more and and more to get the same effects. If one abstains from caffeine for a few weeks, they can't ingest the same amount as they previously did because their adenosine receptors have down-regulated. If the liver is responsible, this means the liver became inefficient again in those few weeks of caffeine abstinence.
Regardless of the mechanism, whether its adenosine receptors or something else, the pattern is the same i.e. when people first take caffeine they feel the full effect and then over time it becomes diminished unless more is taken. The effect of caffeine can be 'reset' given a few weeks of abstinence. This doesn't lend well to the idea that caffeine would be a good indicator of liver health.
Haidut, thanks for mentioning this. My sweat sometimes smells like ammonia, and I noticed that restricting coffee solves this. Is it only the combo high protein/caffeine that causes problems? How do you time protein and caffeine intake? (I am wondering about the long half-life of caffeine.)haidut said:https://raypeatforum.com/forums/posts/98018/ I take it with a glass or orange juice and not much else. I avoid high protein meals with caffeine since it can increase ammonia.
Giraffe said:https://raypeatforum.com/forums/posts/98262/Haidut, thanks for mentioning this. My sweat sometimes smells like ammonia, and I noticed that restricting coffee solves this. Is it only the combo high protein/caffeine that causes problems? How do you time protein and caffeine intake? (I am wondering about the long half-life of caffeine.)haidut said:https://raypeatforum.com/forums/posts/98018/ I take it with a glass or orange juice and not much else. I avoid high protein meals with caffeine since it can increase ammonia.
Do you know of anything else I could try? (Thiamin and Ceylon cinnamon do not help.)
Thanks, haidut. Do you mean you don't have sugar in the coffee, but have O.J. around the same time? And if you avoid coffee around high protein meals, what do you do to inhibit iron absorption with red meat?haidut said:I take it with a glass or orange juice and not much else. I avoid high protein meals with caffeine since it can increase ammonia.
dd99 said:https://raypeatforum.com/forums/posts/98334/Thanks, haidut. Do you mean you don't have sugar in the coffee, but have O.J. around the same time? And if you avoid coffee around high protein meals, what do you do to inhibit iron absorption with red meat?haidut said:I take it with a glass or orange juice and not much else. I avoid high protein meals with caffeine since it can increase ammonia.
supercoolguy said:https://raypeatforum.com/forums/posts/98348/ YEah....Thats what im wondering. No coffee with red meat? have you lost your bloody mind? I also wondered about What and how much MB for reducing NO? Plus i search MB and Serotonin Syndrome pops-up! for SSRI users. But would that include anybody to a degree?
sueq said:https://raypeatforum.com/forums/posts/98352/ Good to know about the caffeine ammonia link. This may change my meal routine. Could milk successfully replace coffee for lowering iron absorption? To the same extent? I am watching an age spot shrink, lighten and break up. An indicator for progress.