Such_Saturation
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Mycotoxins in root extracts of American and Asian ginseng bind estrogen receptors alpha and beta. - PubMed - NCBI
Zearalenone, an Estrogenic Mycotoxin, Is an Immunotoxic Compound
Several Fusarium species produce toxic substances of considerable concern to livestock and poultry producers, namely deoxynivalenol, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS) and zearalenone. Zearalenone is the primary toxin, causing infertility, abortion or other breeding problems, especially in swine.
Zearalenone is heat-stable and is found worldwide in a number of cereal crops, such as maize, barley, oats, wheat, rice, and sorghum.
In addition to its actions on the classical estrogen receptors, zearalenone has been found to act as an agonist of the GPER (GPR30).
A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds. The term "mycotoxin" is usually reserved for the toxic chemical products produced by fungi that readily colonize crops. One mold species may produce many different mycotoxins, and several species may produce the same mycotoxin.
Mycotoxins can appear in the food chain as a result of fungal infection of crops, either by being eaten directly by humans or by being used as livestock feed. Buildings are another source of mycotoxins and people living or working in areas with mold increase their chances of adverse health effects. Mycotoxins in animal fodder, particularly silage, can decrease the performance of farm animals and potentially kill them. Several mycotoxins reduce milk yield when ingested by dairy cattle.Contamination of medicinal plants with mycotoxins can contribute to adverse human health problems and therefore represents a special hazard. Numerous natural occurrences of mycotoxins in medicinal plants and herbal medicines have been reported from various countries including Spain, China, Germany, India, Turkey and from the Middle East. In a 2015 analysis of plant-based dietary supplements, the highest mycotoxin concentrations were found in milk thistle-based supplements.
Zearalenone, an Estrogenic Mycotoxin, Is an Immunotoxic Compound
Several Fusarium species produce toxic substances of considerable concern to livestock and poultry producers, namely deoxynivalenol, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS) and zearalenone. Zearalenone is the primary toxin, causing infertility, abortion or other breeding problems, especially in swine.
Zearalenone is heat-stable and is found worldwide in a number of cereal crops, such as maize, barley, oats, wheat, rice, and sorghum.
In addition to its actions on the classical estrogen receptors, zearalenone has been found to act as an agonist of the GPER (GPR30).
A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds. The term "mycotoxin" is usually reserved for the toxic chemical products produced by fungi that readily colonize crops. One mold species may produce many different mycotoxins, and several species may produce the same mycotoxin.
Mycotoxins can appear in the food chain as a result of fungal infection of crops, either by being eaten directly by humans or by being used as livestock feed. Buildings are another source of mycotoxins and people living or working in areas with mold increase their chances of adverse health effects. Mycotoxins in animal fodder, particularly silage, can decrease the performance of farm animals and potentially kill them. Several mycotoxins reduce milk yield when ingested by dairy cattle.Contamination of medicinal plants with mycotoxins can contribute to adverse human health problems and therefore represents a special hazard. Numerous natural occurrences of mycotoxins in medicinal plants and herbal medicines have been reported from various countries including Spain, China, Germany, India, Turkey and from the Middle East. In a 2015 analysis of plant-based dietary supplements, the highest mycotoxin concentrations were found in milk thistle-based supplements.
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