Understanding the necessity of Resolvins, Protectins, Maresins in resolving inflammation

[Elie]

Has anyone here dove deep to understand these derivatives of omega 3 fatty acids? AKA SPM (Specialized Pro-Resolving Mediators)

Are they all necessary for the resolution of inflammation?

Can inflammation be resolved without them?

If not, what amount of omega 3 is actually necessary?

It seems to be the next "hot" thing in omega three supplements