Rich77
Member
- Joined
- Nov 17, 2018
- Messages
- 17
Hi,
Can someone help with this problem. Thank you.
-Male, 38 yrs old. History of alcohol abuse. During 20 years of alcohol use, always took the proper supplements: B complex, C, E, Multi-minerals +Zn. Also herbs Milk Thistle, Dandelion Coffee, plus weekly intake of 400-500 gm fried liver, etc.
- Over the years, all my liver, lipid, CBC, and other blood profiles show normal ranges. Except for Total Bilirubin > always kind of High (above range).
Serum vitamin A (retinol) persistently on the upper side/80-90 mcg/dL. Other vitamins, mins, all within normal ranges.
Frequent examinations of liver condition (utlra-sound tests) show enlarged liver, possible fatty liver, but not a cause for concern (per physicians, technicians).
Around 4 years ago, and as I been working and living indoors for years (no sun exposure), done vitamin D test. Result: 10 ng (severe deficiency). Took D Drops, also D 300,000 IU injections. None would raise D into sufficient range.
Two years ago, started D 50,000 capsules/weekly. 10 weeks and D went up to 50 ng. Vitamin A (retinol) dropped, first time ever! below 70 mcg/dL. Since the D 50,000 capsules provided calm, better sleep, less long-bones pain. Continued to take but more frequently. From Nov. 15, 2017, to date, took a total of 1 Million IU of vitamin D.
From Jan 2018, totally abstained from alcohol. And here is where things started to go wrong! Lab tests were showing unprecedented abnormalities:
- Total Protein below range 58 g/L (range 61-79).
- ALP persistently below range 48 IU/L (56-119) !
- Trfn.Sat above range 46% (20-40).
- Ferritin persistently at the low end of range 50 ng/mL (24-337).
- Cu persistently at the low end of range 13 umol/L (12.4-31.7)
- Ceruloplasmin persistently at the low end of range 0.24 g/L (0.22-0.58).
Couldn't care less about what those low results meant. But started worrying about my state of health, when my friends and fellow workers at the office noticed abnormalities: pale face, slight yellowing whites of eyes, sudden outbursts over small mistakes, jittery, depressed mood, melancholic. Nothing would make me relax, or laugh. Yet the most visible sign was head hair. Always had healthy head of hair. Suddenly, since about 6 months, started thinning (thou less now, in last few weeks), then the complete change came about: VERY dry, brittle, straw like, kinky hair. Classic look of that kinky hair syndrome. Must be something internal, within the body, that went haywire! Couldn't tell what it was.
Doing extensive search on the web, early in the year. No answers. This is very obvious kinky hair condition. Kinky hair a syndrome of Menkes disease, but it is a genetic disease in new born, not in adults!
Then I saw one site healthsupplementsnutritionalguide mention Copper as a nutritional cause of dry brittle hair (though my hair condition is nothing as simple dry/brittle, but obvious look of some serious physiological disorder).
With low Cu blood test results in mind, started daily intake of all sorts of copper sources. Cu 2 to 4 mg caps/day. Half cup of Sesame seeds. Half cup Almonds. 50-100 gm of 80% dark chocolate bar. Yet after many months on high Cu intake, and stopping Zn (not needed after abstaining from alcohol), and vitamin C. Both of those are Cu antagonists, the Cu/Cp/Ferritin all remain low!
What is going on? How to explain this.
I've read somewhere, low ALP is possible indicator of excess vit D in the body. May be.
That low Ferritin may relate to low Retinol levels. But A is well within normal range, if not in the upper range.
Had a chat over the weekend with one doctor, sent him my lab results. Amazed. Says, these are signs of malnutrition! "You can't be malnourished! In underdeveloped, poor nations, yes, but not here"!
Where does all the copper in copper-rich foods go? Low Cp and Cu, are definite indicator of Cu deficiency. Stopping Zn, and C supplements (except for 4 oranges+ 2 limes per day to compensate for vit C). Why the body can't absorb copper?
Does too much copper intake, causes reduction in Cp?
Does copper toxicity, shows up in tests as deficiency? As a page in MayoClinic lab suggest.
How can Ferritin be low range when serum Fe is high?
*Latest CBC panel - nothing abnormal (like leukopenia/low WBC - indicator of low Cu) detected.
Can someone help with this problem. Thank you.
-Male, 38 yrs old. History of alcohol abuse. During 20 years of alcohol use, always took the proper supplements: B complex, C, E, Multi-minerals +Zn. Also herbs Milk Thistle, Dandelion Coffee, plus weekly intake of 400-500 gm fried liver, etc.
- Over the years, all my liver, lipid, CBC, and other blood profiles show normal ranges. Except for Total Bilirubin > always kind of High (above range).
Serum vitamin A (retinol) persistently on the upper side/80-90 mcg/dL. Other vitamins, mins, all within normal ranges.
Frequent examinations of liver condition (utlra-sound tests) show enlarged liver, possible fatty liver, but not a cause for concern (per physicians, technicians).
Around 4 years ago, and as I been working and living indoors for years (no sun exposure), done vitamin D test. Result: 10 ng (severe deficiency). Took D Drops, also D 300,000 IU injections. None would raise D into sufficient range.
Two years ago, started D 50,000 capsules/weekly. 10 weeks and D went up to 50 ng. Vitamin A (retinol) dropped, first time ever! below 70 mcg/dL. Since the D 50,000 capsules provided calm, better sleep, less long-bones pain. Continued to take but more frequently. From Nov. 15, 2017, to date, took a total of 1 Million IU of vitamin D.
From Jan 2018, totally abstained from alcohol. And here is where things started to go wrong! Lab tests were showing unprecedented abnormalities:
- Total Protein below range 58 g/L (range 61-79).
- ALP persistently below range 48 IU/L (56-119) !
- Trfn.Sat above range 46% (20-40).
- Ferritin persistently at the low end of range 50 ng/mL (24-337).
- Cu persistently at the low end of range 13 umol/L (12.4-31.7)
- Ceruloplasmin persistently at the low end of range 0.24 g/L (0.22-0.58).
Couldn't care less about what those low results meant. But started worrying about my state of health, when my friends and fellow workers at the office noticed abnormalities: pale face, slight yellowing whites of eyes, sudden outbursts over small mistakes, jittery, depressed mood, melancholic. Nothing would make me relax, or laugh. Yet the most visible sign was head hair. Always had healthy head of hair. Suddenly, since about 6 months, started thinning (thou less now, in last few weeks), then the complete change came about: VERY dry, brittle, straw like, kinky hair. Classic look of that kinky hair syndrome. Must be something internal, within the body, that went haywire! Couldn't tell what it was.
Doing extensive search on the web, early in the year. No answers. This is very obvious kinky hair condition. Kinky hair a syndrome of Menkes disease, but it is a genetic disease in new born, not in adults!
Then I saw one site healthsupplementsnutritionalguide mention Copper as a nutritional cause of dry brittle hair (though my hair condition is nothing as simple dry/brittle, but obvious look of some serious physiological disorder).
With low Cu blood test results in mind, started daily intake of all sorts of copper sources. Cu 2 to 4 mg caps/day. Half cup of Sesame seeds. Half cup Almonds. 50-100 gm of 80% dark chocolate bar. Yet after many months on high Cu intake, and stopping Zn (not needed after abstaining from alcohol), and vitamin C. Both of those are Cu antagonists, the Cu/Cp/Ferritin all remain low!
What is going on? How to explain this.
I've read somewhere, low ALP is possible indicator of excess vit D in the body. May be.
That low Ferritin may relate to low Retinol levels. But A is well within normal range, if not in the upper range.
Had a chat over the weekend with one doctor, sent him my lab results. Amazed. Says, these are signs of malnutrition! "You can't be malnourished! In underdeveloped, poor nations, yes, but not here"!
Where does all the copper in copper-rich foods go? Low Cp and Cu, are definite indicator of Cu deficiency. Stopping Zn, and C supplements (except for 4 oranges+ 2 limes per day to compensate for vit C). Why the body can't absorb copper?
Does too much copper intake, causes reduction in Cp?
Does copper toxicity, shows up in tests as deficiency? As a page in MayoClinic lab suggest.
How can Ferritin be low range when serum Fe is high?
*Latest CBC panel - nothing abnormal (like leukopenia/low WBC - indicator of low Cu) detected.