This was originally posted on longecity and I am posting it here to encourage k2 discussion.
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Vitamin K2 and D in Patients With Aortic Valve Calcification: A Randomized Double-Blinded Clinical Trial
Axel C.P. Diederichsen,
Jes S. Lindholt,
Sören Möller,
Kristian A. Øvrehus,
Søren Auscher,
Jess Lambrechtsen,
Susanne E. Hosbond,
Dilek H. Alan,
… See all authors
Originally published25 Apr 2022https://doi.org/10.1...NAHA.121.057008Circulation. 2022;145:1387–1397
https://www.ahajourn...aortic stenosis.
A noncontrast cardiac CT scan was obtained at baseline, and repeated after 1 and 2 years of intervention.
This result will be disbelieved or questioned by some in the K2 community, but this trial seems seems very well-designed and executed AFAICT.
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Vitamin K2 and D in Patients With Aortic Valve Calcification: A Randomized Double-Blinded Clinical Trial
Axel C.P. Diederichsen,
Jes S. Lindholt,
Sören Möller,
Kristian A. Øvrehus,
Søren Auscher,
Jess Lambrechtsen,
Susanne E. Hosbond,
Dilek H. Alan,
… See all authors
Originally published25 Apr 2022https://doi.org/10.1...NAHA.121.057008Circulation. 2022;145:1387–1397
https://www.ahajourn...aortic stenosis.
In a randomized, double-blind, multicenter trial, men from the community with an AVC score >300 arbitrary units (AU) on cardiac noncontrast computer tomography were randomized to daily treatment with tablet 720 µg MK-7 plus 25 µg vitamin D or matching placebo for 24 months...The progression in aortic and coronary artery calcification score was not significantly different between patients treated with MK-7 plus vitamin D and patients receiving placebo.
A noncontrast cardiac CT scan was obtained at baseline, and repeated after 1 and 2 years of intervention.
The progression in aortic and coronary artery calcification score was not significantly different between patients treated with MK-7 plus vitamin D and patients receiving placebo.
This result will be disbelieved or questioned by some in the K2 community, but this trial seems seems very well-designed and executed AFAICT.