Almost every time I take ibuprofen I have euphoria like feeling, especially when taking before bed. The most precise feeling to describe this experience - is like I am light as feather and i am diving through the clouds when taking before sleep. Literally something clicks in my head , and I feel such a huge relief and can think better and my mind is so much clearer, as well as whole body immediately become lighter. Naproxen have even more profound effect. I believe i have some chronic inflammation... ibuprofen make me feel ''normal''.