I wonder why the guys on hackstasis are having success treating their pfs? They say it works fast and effectively to bring their libido and energy back up to par. The drawback is they complain about what seems to them to be high prolactin and/or adrenaline issues.
Do you think it supresses cortisol, raises prolactin, and stimulates GABA?
The mental effects of PFS are mostly depression, due to high cortisol and lower allopregnanolone. Cortisol antagonists like RU486 have been successfully used for intractable depression for years and in addition a cortisol antagonist would remove the block on gonadal steroidogenesis, including T/DHT, and improve overall metabolism. I do not see how using RU486 is incompatible or different with all the anti-cortisol measures Peat has spoken about. It is simply a synthetic cortisol blocker, while Peta prefers the endogenous ones like progesterone, pregnenolone, DHEA, thyroid, etc.