WARNING! Old People Take Baths In Public Jacuzzis

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“Many babies are being given milk substitutes (health food drinks) made from soy or rice, with terrible consequences. The same products used by adults have less disastrous effects in the short term, but are still likely to contribute to degeneration and dementia.” -Ray Peat
 
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“Increased intracellular calcium, in association with excess nitric oxide and excitatory amino acids, is involved in several neurodegenerative diseases, including ALS, Alzheimers disease, Parkinsons disease, Huntingtons chorea, and epilepsy. Magnesium, nicotine, progesterone, and many other substances are known to protect against excitotoxic calcium overload, but there is no coherent effort in the health professions to make rational use of the available knowledge.” -Ray Peat
 
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Peat: Yeah. And the calcium in meat is very low, it's as high as 10/1 phosphate over calcium.

Andrew: Describe the cellular aging effects of phosphate and how we, as consumers of phosphate, can be harming ourselves if not careful ?

Peat: In the last few years, a strange mutant mouse was discovered; they named it “klotho” for a Greek fate; this mutant mouse aged very rapidly and had most of the features of human aging, such as decreased lung function, respiratory failure, hardening of the arteries, osteoporosis, wrinkling of the skin, all of the basic things we think of as aging (calcification generally; deposition of calcium phosphate where it shouldn't be while taking it out of bones where it should be).

Andrew: So that's the aging process in general, you just described

Sarah: So excess dietary phosphate is one of the factors in the aging processes

 
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Andrew: Kidney disease, and kidney burden can be caused by phosphate overload. How to eat better and get a better calcium/phosphate?

Peat: Lots of doctors for years have recommended cutting down on your calcium intake to avoid calcification. But actually, that’s the same sort of reasoning that they know that calcium excites cells, and so they say cut down calcium (if you have seizures, or high blood pressure, or whatever). But it turns out that’s a whole aspect of calcium that has been neglected; if you are deficient in calcium you tend to get cramps, might have seizures, bronchial spasms, asthma. The lack of calcium excites tissues, turns on the excitotoxic mediators, triggers inflammation, and sets up the conditions for depositing calcium. So, when you're low in calcium in your diet, you're setting up conditions, increasing the parathyroid hormone for example, to take calcium out of your bones to make up for what you're not eating. And the parathyroid hormone releases serotonin, among other things, and histamine, causing more inflammation, more calcification of the tissues, more tendency for the calcium to combine with phosphate and settle into the arteries, kidneys, brain cells, everywhere except the bones.

Sarah: So a calcium-deficient diet is really associated with the stimulation of a lot of inflammatory mediators ?

Peat: Yeah. In fact, the tone of the small arteries is very responsive to calcium. So, if you're low in calcium, your blood pressure goes up. And for about 30 years, David McCarron has been saying it's not sodium that causes high blood pressure, it's calcium deficiency. So, eating extra calcium can often cure hypertension. Or, avoiding excess phosphate in the diet. Or, a good ratio; for example one of the things that started getting me interested in phosphate was looking at the fat-free diet that George Burr and a group did in the 1930s; they believed that unsaturated fatty acids were nutritionally essential. So, one of their group, William Brown, went on a 6-month fat-free diet, where his diet consisted of nothing but a total of 2500 calories a day, made up basically of sugar, syrup, for several meals; and for supper, fat-free cottage cheese with a small potato starch biscuit and half an orange. So basically it was a sugar and milk diet, a gallon total of milk, some of it made into cottage cheese for his dinner, for 6 months. He had chronically life-long migraines headaches every week; and at work, he experienced a normal amount of fatigue at the end of the day. And he had hypertension, 150 over a 100 sometimes. His cholesterol was 250 and he was about 10 pounds overweight. But a few months into his diet, the sugar and milk diet, his cholesterol had come down about 50 points, his weight stabilized about 10 pounds lower, his blood pressure came down to normal; and he never again had migraine headaches.
One of the things they kept talking about in the article was that, surprisingly, at the end of the work day, he wasn't tired.

 
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“Dr. Abram Hoffer, famous for his use of niacin in the treatment of schizophrenia and depression, has reported 1,000 mg of niacin taken three times a day can improve memory and correct some senility problems. In one of his studies involving 10 people suffering from senility, five totally recovered, two had significant improvement, and three had no noticeable improvement.”

 
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“"Encephalopathy" means damage or disease that affects the brain. It happens when there’s been a change in the way your brain works or a change in your body that affects your brain. Those changes lead to an altered mental state, leaving you confused and not acting like you usually do.

Encephalopathy is not a single disease but a group of disorders with several causes. It’s a serious health problem that, without treatment, can cause temporary or permanent brain damage.

It’s easy to confuse encephalopathy with encephalitis. The words sound similar, but they are different conditions. In encephalitis, the brain itself is swollen or inflamed. Encephalopathy, on the other hand, refers to the mental state that can happen because of several types of health problems. But encephalitis can cause encephalopathy.

Causes and Types​

There are two main types of encephalopathy: reversible and irreversible. Reversible causes include:

  • Hepatic encephalopathy. When your liveris unable to remove toxins from your bloodas well as it should, they build up in your body. That makes it hard for your brain to work well. It can happen to people with a chronic liver disease like cirrhosis or after an overdose of acetaminophen or other medications.
  • Hashimoto’s encephalopathy. This type is linked to a thyroid condition called Hashimoto’s disease. The cause isn’t clear, but it may be that your immune systemattacks your brain and changes the way it works.
  • Metabolic encephalopathy. This happens when another health condition, such as diabetes, liver disease, kidney failure, or heart failure, makes it hard for the brain to work. For example, if blood sugar gets too high in diabetes, it can lead to confusion and even a coma.
  • Infections of the brain, such as encephalitis or meningitis, or in another part of the body, such as a urinary tract infection. An extreme response to an infection, called sepsis, can also lead to encephalopathy.
  • Brain tumors
  • Long-term exposure to toxins like solvents, drugs, radiation, paints, industrial chemicals, and some metals
  • Nonconvulsive status epilepticus. This happens when you have seizures over and over in your brain, though they may not cause any physical symptoms.“

 
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“What is encephalopathy caused by?


Hepatic encephalopathy can be caused by a chronic liver condition such as cirrhosis, an infection, overdose of prescription medications, or bleeding in the digestive tract. chronic traumatic encephalopathy (CTE) — this is probably caused by repeated blows to the head and concussions.”

“What are the symptoms of encephalopathy?​

The symptoms of encephalopathy vary from person to person.

The most common symptom of encephalopathy is a change in mental state, with problems such as:

  • loss of memory
  • reduced ability to think clearly or concentrate
  • drowsiness
  • changes in personality such as irritability, aggression, impulsive behaviour or having suicidal thoughts
Some people might also have:

There are several different patterns of encephalopathy. Some people have acute encephalopathy, which comes on fairly quickly and can go away. Others have chronic encephalopathy, which tends to develop slowly and does not go away.

Some people with chronic underlying conditions, such as liver disease, can be well at times and then have an episode of encephalopathy triggered by an infection, bleeding in the digestive tract, alcohol, medications, or an electrolyte imbalance.

Some encephalopathies cause permanent damage to the brain, while others do not. Some can be fatal.“

 
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Encephalitis is different from encephalopathy….


Encephalitis is most often due to a virus, such as:

Encephalitis caused by a virus is known as "viral encephalitis". In rare cases, encephalitis is caused by bacteria, fungi or parasites.

You can catch these infections from someone else, but encephalitis itself is not spread from person to person.



 
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Problems with the immune system​

The immune system protects the body from illness and infection. When germs enter the body, the immune system attacks them to stop them causing a serious infection.

But very rarely something goes wrong with the immune system and it mistakenly attacks the brain, causing encephalitis.

This can be triggered by:

  • a previous infection in another part of the body (which usually happens a few weeks earlier)
  • a non-cancerous or cancerous growth (tumour) somewhere in the body
  • a vaccination (this is very rare and the benefits of vaccination far outweigh the risk of encephalitis)
 
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“Energy depletion leads to brain atrophy, but with normal stimulation and nutrition even adult brains can grow.” -Ray Peat
 
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“Normally, just being awake makes enough adrenaline to mobilize as much glucose from your stores as you need. But when you run out of that stored sugar, your brain still requires sugar to function properly. So, instead of just increasing the adrenaline more and more, when the adrenaline reaches a certain level and can’t get the blood sugar up from storage, then you turn on the cortisol. And that’s the classic stress that can be harmful, because the cortisol dissolves first tissues which are very fragile (like the thymus — that starts turning to sugar immediately when you run out of stored glycogen). And when the thymus is gone in just two or three hours of intense stress, that happens to be one of the reasons they think adults don’t have thymus glands, because by the time they’re dead and are analyzed, the thymus has been eaten up by stress; they might have had a perfectly normal thymus until they were sick and dead.

After the thymus is consumed and turned to sugar, the cortisol starts breaking down your muscles, then your skin. The brains, lungs and heart are spared from stress, partly because in a healthy person they are very saturated with androgens (testosterone and DHEA especially) which block the breakdown function of cortisol. If your brain, lungs and heart are short of those protective steroids then that’s where the stress really starts causing severe, deadly damage. The post-traumatic stress disorder is produced when someone has had such terrible stress, such as being tortured or being in terrific catastrophes, that they not only deplete their stored glycogen and breakdown the expendable tissues like thymus and liver, but then the cortisol starts damaging the brain and heart, and so on. So they get very severe chronic symptoms. Once the stress is completely resolved, then the brain can massively regenerate itself. For example they’ve seen MRIs of girls who have been in anorexia for months, their brain shrinks from living on the cortisol breaking down their tissues, but when they start eating the brain can rebuild itself in just a few weeks.” -Ray Peat
 
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“And things that increase your carbon dioxide work right along with vitamin K in helping to keep the calcium and phosphate in your bones rather than in your arteries. Even baking soda helps to build strong bones. And in the way it's acting, it's the same as vitamin K or niacinamide; it's helping the kidneys to excrete phosphate that you don't need, helping to deposit calcium and phosphate in the bones, while taking it out of arteries.” -Ray Peat

 
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“Cows pass their immunity to their offspring by colostrum, and various colostrum products are on the market to achieve passive immunity. Additional sources of antibody products can be utilized in a similar manner to achieve passive immunity. These are from avian sources such as chickens. In birds, passive transfer of immunity occurs through the egg.”


“Just as immune protection is transferred in utero in mammals or passively by a lactating mother via colostrum, hens passively transfer protection to their young by secreting immunoglobulin and other immune factors into their eggs for use by the hatching chick. The transfer of chicken immunoglobulins from the hen’s serum to the yolk and from the yolk to the chick is analogous to cross-placental transfer of IgG from the mammalian mother to its offspring.”

 
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“Milk and fruit juice are osmotically balanced with minerals and sugar, so they don't cause imbalance of body fluids, the way drinking plain water can in a hypothyroid person. Many doctors have recommended drinking a certain amount of water every day, regardless of thirst, and that often causes problems in people with hormonal problems.” -Ray Peat

 
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The short video in this link is worth watching. I found the commenters at the bottom worth reading too, about supplementing zinc….

0This TED talk by Julia J Rucklidge, Professor of Clinical Psychology in the Department of Psychology at the University of Canterbury, discusses the power of nutrition and supplements. She explores a range of scientific research showing the significant role that nutrition plays when it comes to mental health or illness:”

 
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“An excess of tryptophan early in life, stress, or malnutrition, activates the system for converting tryptophan into serotonin, and that tendency persists into adulthood, modifying pituitary function, and increasing the incidence of pituitary and other cancers.

Serotonin's contribution to high blood pressure is well established. It activates the adrenal cortex both directly and through activation of the pituitary. It stimulates the production of both cortisol and aldosterone. It also activates aldosterone secretion by way of the renin-angiotensin system. Angiotensin is an important promoter of inflammation, and contributes to the degeneration of blood vessels with aging and stress. It can also promote estrogen production.”
-Ray Peat

“Carbon dioxide, high altitude, thyroid, progesterone, caffeine, aspirin, and decreased tryptophan consumption protect against excessive serotonin release. When sodium intake is restricted, there is a sharp increase in serotonin secretion. This accounts for some of the antiinflammatory and diuretic effects of increased sodium consumption--increasing sodium lowers both serotonin and adrenalin.” -Ray Peat

 
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“A diet that provides enough calcium to limit activity of the parathyroid glands, and that is low in phosphate and polyunsaturated fats, with sugar rather than starch as the main carbohydrate, possibly supplemented by niacinamide and aspirin, should help to avoid some of the degenerative processes associated with high phosphate: fatigue, heart failure, movement discoordination, hypogonadism, infertility, vascular calcification, emphysema, cancer, osteoporosis, and atrophy of skin, skeletal muscle, intestine, thymus, and spleen (Ohnishi and Razzaque, 2010; Shiraki-Iida, et al., 2000; Kuro-o, et al., 1997; Osuka and Razzaque, 2012). The foods naturally highest in phosphate, relative to calcium, are cereals, legumes, meats, and fish. Many prepared foods contain added phosphate. Foods with a higher, safer ratio of calcium to phosphate are leaves, such as kale, turnip greens, and beet greens, and many fruits, milk, and cheese. Coffee, besides being a good source of magnesium, is probably helpful for lowering phosphate, by its antagonism to adenosine (Coulson, et al., 1991).” -Ray Peat

 
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“Although increased phosphate generally causes vascular calcification (increasing rigidity, with increased systolic blood pressure), when a high level of dietary phosphate comes from milk and cheese, it is epidemiologically associated with reduced blood pressure (Takeda, et al., 2012).” -Ray Peat

 
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“A meeting of anaesthetists in Singapore heard that while many patients experience confusion after waking from operations, one-third, or about 264,000, of the 800,000 Australians over 65 having operations each year are showing cognitive deficits one week after surgery. And about one in five or 160,000 people over the age of 65 are still suffering mentally three months on.
Lis Evered, the research manager of the Centre for Anaesthesia and Cognitive Function at St Vincent’s Hospital in Melbourne, said studies also suggested surgery could be triggering dementia in people who have subtle memory loss before surgery. Associate Professor Evered told the conference that a study of 67 Victorians with mild cognitive impairment before surgery showed 43 per cent of them had dementia one year on.
‘‘In the older population, you would expect 10 to 15 per cent who have mild cognitive impairment to progress to dementia over 12 months and we saw 43 per cent, which is significantly higher,’’ she said.
Beverley Orser, a professor of anaesthesia and physiology at the University of Toronto, said while post-operative cognitive decline was occurring in people irrespective of the type of surgery they were having and the anaesthetic used, it was more common among older people and those having longer procedures. It was also more likely to occur in people having multiple operations and suffering infections.“
 
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