Low Toxin Studies When you realize that two doctors named DeWitt Goodman and Frank Rees Smith solved the Vitamin A toxicity epidemic in the 1970s, and nobody listened.

[charlie]

When you realize that two doctors named DeWitt Goodman and Frank Rees Smith solved the Vitamin A toxicity epidemic in the 1970s, and nobody listened.Rest in peace, guys. We got this for you.

View: https://x.com/MicroBerto/status/1773905595269009735?s=20

Smith and Goodman published a TON of studies, but the few that really nailed it for me (so far) are these three:

1. 1971 - “The Effects of Diseases of the Liver, Thyroid, and Kidneys on the Transport of Vitamin A in Human Plasma.” https://ncbi.nlm.nih.gov/pmc/articles/PMC292185/ (full-text PDF at https://ncbi.nlm.nih.gov/pmc/articles/PMC292185/pdf/jcinvest00199-0200.pdf)

Here, they correlate RBP with serum retinol, but see how they fluctuate in different disease states. Renal disease has RBP go up, but LIVER disease has RBP go down. They figure out that these aren't the best biomarkers, but something goes wrong in liver disease that REDUCES serum retinol and RBP (basically destroying anyone who thinks low serum retinol is a sign of vitamin A "deficiency").

This study was so ahead of its time.

2. 1973 - "Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. I. A functional defect in hepatic retinol release"https://sciencedirect.com/science/article/abs/pii/S0002916523333677

Here, they basically cure "vitamin A deficiency" by merely giving children protein and calories. No protein = no RBP = low serum retinol = bad news once retinyl esters start to rise... which leads you to study

3. 1976 - “Vitamin A Transport in Human Vitamin A Toxicity.” https://nejm.org/doi/full/10.1056/NEJM197604082941503

Here, they realize that serum retinyl esters bound to LDL are what begin circulating once you're vitamin A toxic, and that these poorly-wrapped molecules are the real homewreckers.

That's basically it dude. Feed protein and zinc, stop overloading vitamin A, get your body to stop dumping retinyl esters into circulation, and you've solved a LOT of the world's problems.

After that, Goodman went heavily into the LDL world (not surprised why at this point), Smith ventured into other areas of vitamins, etc... I'm sure there's more really good stuff they published.

If they were really loud individuals living in this day and age, they may have been social media pariahs (superstars in our minds). Who knows. But they just seemed to publish tons of research and moved on to the next thing. Maybe this is wrong, I'm not gonna read all 300 studies they put out.

But I'm always fascinated by dudes who just figured it out, and really early at that, even if they may not have realized how critical it is what they figured it out. Geniuses in my book, regardless of whatever else they got into later on.

View: https://x.com/MicroBerto/status/1774093059623432629?s=20

 

[Daniel North]

View: https://x.com/MicroBerto/status/1774272541361606694?s=20


This made me check my own LDL levels, and interestingly:

 

[PopSocket]

View: https://x.com/MicroBerto/status/1774272541361606694?s=20


This made me check my own LDL levels, and interestingly:

View attachment 62202

You are low A since July 2023 ?

 

[Daniel North]

Since oct 16th 2023

Low Toxin Logs - Log - Anti-Vitamin A Diet - Testing out if i have been a Peatard

I've decided to test out the Anti-Vitamin A diet. I've been on it since 18th Oct 2023. About a week now The reason I became motivated to test this diet out is because of some recent health problems only the Anti-Vitamin A Theory offers an explanation too. One can read and discuss as much as...

raypeatforum.com

 

[Peater]

I found this in the replies:


View: https://twitter.com/bilbobookends/status/1774872911054299546

 

[Dr. B]

I found this in the replies:


View: https://twitter.com/bilbobookends/status/1774872911054299546

Didnt someone say skim milk has vitamin A thats bound to the casein or something like that? That source actually states the skim milk they used still had 0.5% fat in it, which is significant because even whole milk as they mention is only 3.5% fat. So do skim milk, fat free yogurts and cheeses and whey still contain vitamin A even if they are zero fat?

 

[htuoyabc]

Interesting! What ratio of Triglycerides to HDL should we shoot for? After going low poison A my LDL dropped, my HDL is about the same, but my Triglycerides have gone up.

 

[Blossom]

Didnt someone say skim milk has vitamin A thats bound to the casein or something like that? That source actually states the skim milk they used still had 0.5% fat in it, which is significant because even whole milk as they mention is only 3.5% fat. So do skim milk, fat free yogurts and cheeses and whey still contain vitamin A even if they are zero fat?

Binding of vitamin A with milk α- and β-caseins

The binding sites of retinol and retinoic acid with milk α- and β-caseins were determined, using constant protein concentration and various retinoid c…

www.sciencedirect.com

Binding of vitamin A by casein micelles in commercial skim milk

Recent studies have shown that reassembled micelles formed by caseinates and purified casein fractions (αs- and β-casein) bind to hydrophobic compounds, including curcumin, docosahexaenoic acid, and vitamin D. However, limited research has been done on the binding of hydrophobic compounds by...

www.journalofdairyscience.org

 

[DanDare]

Norman F Childers fixed his arthritis pain that started badly when he was age 50. He avoided whole nightshade family and anything fortified vit a and vit d as on the front page. He lived to 100. His book was released sometime in the 70's .

 

[Osukhan]

Norman F Childers fixed his arthritis pain that started badly when he was age 50. He avoided whole nightshade family and anything fortified vit a and vit d as on the front page. He lived to 100. His book was released sometime in the 70's .

very cool find