ecstatichamster
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- Nov 21, 2015
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I would like to put it on a tendon , any suggestions as to solvents?
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Oxidal has salicylic acid. Maybe the same solvents for aspirin would work. 80 water 20 ethyl alcohol.I would like to put it on a tendon , any suggestions as to solvents?
"Aspirin (acetyl salicylic acid, USP) powder was dissolved in isopropyl alcohol or ethanol and propylene glycol (1.7:1 volvol) to a final concentration
of 94 mg/mL. Preliminary studies demonstrated that aspirin was stable in this vehicle, with <1% salicylate detected after 24 hours at room temperature. The aspirin preparation was made daily immediately before its application. Volunteers attended the pharmacy where the preparation was applied and were asked not to wash the area for at least 12 hours. The aspirin solution was applied to the forearm and upper arm over a 15-minute interval."
Isnt propylene glycol anti-freeze?"Aspirin (acetyl salicylic acid, USP) powder was dissolved in isopropyl alcohol or ethanol and propylene glycol (1.7:1 volvol) to a final concentration
of 94 mg/mL. Preliminary studies demonstrated that aspirin was stable in this vehicle, with <1% salicylate detected after 24 hours at room temperature. The aspirin preparation was made daily immediately before its application. Volunteers attended the pharmacy where the preparation was applied and were asked not to wash the area for at least 12 hours. The aspirin solution was applied to the forearm and upper arm over a 15-minute interval."
Why would it matter if it changes the freezing point?Isnt propylene glycol anti-freeze?
Would it be safe long run?
I don't like mct oil. Stains my clothesDoes it mix with MCT oil? Actually, yes?
STABLE ASPIRIN-CONTAINING PREPARATIONS FOR EXTERNAL USE
"The stabilizing agents of the present invention are selected from substances having ability to dissolve Aspirin, too and for example, an ester of an organic acid having 2 to 20 carbon atoms, a glycerol fatty acid ester, silicon oil, hydrocarbon oil and crotamiton are used, and in general one substance or more selected from them are used. [0014] Examples of the organic acids of esters of organic acids having 2 to 20 carbon atoms are myristic acid, lauric acid, oleic acid, sebacic acid, palmitic acid, caprylic acid, isooctanoic acid, stearic acid, isostearic acid, acetic acid, propionic acid, isopalmitic acid, undecylic acid, linoleic acid, linolenic acid, adipic acid, salicylic acid, benzoic acid, lactic acid, caproic acid, eicosanic acid, etc., preferably myristic acid, oleic acid, sebacic acid, palmitic acid, isooctanoic acid, isostearic acid and adipic acid, more preferably myristic acid, oleic acid, sebacic acid and adipic acid. Examples of the 5 esters of the organic acids are esters with an aliphatic monoalcohol, such as methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, hexyl ester, octyl ester, decyl ester, cetyl ester, isocetyl ester, stearyl ester, isostearyl ester, oleyl ester, etc. [0015] Examples of the glycerol fatty acid esters are a plant oil, such as soy bean oil, almond oil, sesame oil, olive oil, camellia oil, corn oil, coconuts oil, etc., an animal oil, such as whale oil, lard, beef tallow, lever oil, etc., triacetin(glycerol 10 triacetate), a middle chain-fatty acid triglyceride, glycerol triisooctanoate, etc., preferably soy bean oil, almond oil, sesame oil, triacetin, a middle chain-fatty acid triglyceride and glycerol triisooctanoate, more preferably soy bean oil, almond oil and a middle chain-fatty acid triglyceride. [0016] Examples of the hydrocarbon oils are liquid paraffin, squalane, squalene, etc., preferably liquid paraffin and squalane. 15 [001 7] The stabilizing agents of the present invention do not only stabilize Aspirin, but also dissolve Aspirin. Therefore, in mixing the stabilizing agent in external preparations, it has enhancing effect of absorption of Aspirin from skin and it is very preferable."
I tried this out and can confirm that aspirin does dissolve in mct oil. Will be testing this our going forward for skin and hair.Does it mix with MCT oil? Actually, yes?
STABLE ASPIRIN-CONTAINING PREPARATIONS FOR EXTERNAL USE
"The stabilizing agents of the present invention are selected from substances having ability to dissolve Aspirin, too and for example, an ester of an organic acid having 2 to 20 carbon atoms, a glycerol fatty acid ester, silicon oil, hydrocarbon oil and crotamiton are used, and in general one substance or more selected from them are used. [0014] Examples of the organic acids of esters of organic acids having 2 to 20 carbon atoms are myristic acid, lauric acid, oleic acid, sebacic acid, palmitic acid, caprylic acid, isooctanoic acid, stearic acid, isostearic acid, acetic acid, propionic acid, isopalmitic acid, undecylic acid, linoleic acid, linolenic acid, adipic acid, salicylic acid, benzoic acid, lactic acid, caproic acid, eicosanic acid, etc., preferably myristic acid, oleic acid, sebacic acid, palmitic acid, isooctanoic acid, isostearic acid and adipic acid, more preferably myristic acid, oleic acid, sebacic acid and adipic acid. Examples of the 5 esters of the organic acids are esters with an aliphatic monoalcohol, such as methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, hexyl ester, octyl ester, decyl ester, cetyl ester, isocetyl ester, stearyl ester, isostearyl ester, oleyl ester, etc. [0015] Examples of the glycerol fatty acid esters are a plant oil, such as soy bean oil, almond oil, sesame oil, olive oil, camellia oil, corn oil, coconuts oil, etc., an animal oil, such as whale oil, lard, beef tallow, lever oil, etc., triacetin(glycerol 10 triacetate), a middle chain-fatty acid triglyceride, glycerol triisooctanoate, etc., preferably soy bean oil, almond oil, sesame oil, triacetin, a middle chain-fatty acid triglyceride and glycerol triisooctanoate, more preferably soy bean oil, almond oil and a middle chain-fatty acid triglyceride. [0016] Examples of the hydrocarbon oils are liquid paraffin, squalane, squalene, etc., preferably liquid paraffin and squalane. 15 [001 7] The stabilizing agents of the present invention do not only stabilize Aspirin, but also dissolve Aspirin. Therefore, in mixing the stabilizing agent in external preparations, it has enhancing effect of absorption of Aspirin from skin and it is very preferable."
That's great, report back how it works for you. How much aspirin did you use, and how much mct?I tried this out and can confirm that aspirin does dissolve in mct oil. Will be testing this our going forward for skin and hair.
Did you add clove and thyroid for a therapeutic purpose, or for aroma?I think the dropper is about 2 ounces so almost 2 oz of mct and just over 1g of aspirin (kinda free poured it) as well as clove and thyme oil (4 drops each)
More for therapeutic than aroma but it’s an interesting scent. They are synergistic and thyme oil is supposed to be pro-progesteroneDid you add clove and thyroid for a therapeutic purpose, or for aroma?