L-lysine - Serotonin Antagonist

[Theo]

I started taking arginine when I read how cardiologist were recommending it to patients and also as a preventative to heart disease.
I later read that arginine combined with lysine is considered a combo that is conducive to relaxing anxieties.
I also read that Dr Slagle has been taking p5p and tyrosine as a mood aide for at least 2 decades.
Lysine , p5p and tyrosine seem to all work together in reducing unproductive stress. That's been my experience. I take 50 mg p5p and 500 mg of tyrosine upon arising and find its very helpful for mood and motivation.

 

[haidut]

I started taking arginine when I read how cardiologist were recommending it to patients and also as a preventative to heart disease.
I later read that arginine combined with lysine is considered a combo that is conducive to relaxing anxieties.
I also read that Dr Slagle has been taking p5p and tyrosine as a mood aide for at least 2 decades.
Lysine , p5p and tyrosine seem to all work together in reducing unproductive stress. That's been my experience. I take 50 mg p5p and 500 mg of tyrosine upon arising and its very helpful for mood and motivation.

Arginine is actually quite dangerous as it is the main precursor to NO. Basically, you are taking an over the counter Viagra and that drug has been tried for heart issue prevention and it failed miserably long term and also increased cancer incidence. I would drop any arginine supplementation beyond what you are getting from food.

 

[Theo]

What about citrulline malate which creates arginine ? Same idea ? Steer clear of it ?
I do like the malate or malic acid. I have taken malic acid supps with good results.

PS i thought NO was good. Apparently not so.
This was my source about NO..
https://m.facebook.com/SinatraMD/posts/660501357334398

 

[haidut]

What about citrulline malate which creates arginine ? Same idea ? Steer clear of it ?
I do like the malate or malic acid. I have taken malic acid supps with good results.

PS i thought NO was good. Apparently not so.
This was my source about NO..
https://m.facebook.com/SinatraMD/posts/660501357334398

Elevated levels of NO are carcinogenic and powerfully suppress metabolism. NO associated with cytochrome C and prevents it from doing its job. Many of the drugs mentions by Peat lower NO. Aspirin, methylene blue, niacinamide, B6, etc all do that. I suggest you read some Peat's articles on his website. Then many things will start making sense.
If elevated NO was good then why is Viagra implicated in heart failure, heart attacks and cancer?

 

[Theo]

Haidut,

I'm on board with what you are saying. Albeit some of it is new information to me.

Question...beta alanine also seems to dilute blood vessels..by a different pathway ?
It does this without increasing NO ?

BTW, i have tried citrulline and arginine and I found beta alanine gave me better results.

 

[haidut]

Haidut,

I'm on board with what you are saying. Albeit some of it is new information to me.

Question...beta alanine also seems to dilute blood vessels..by a different pathway ?
It does this without increasing NO ?

BTW, i have tried citrulline and arginine and I found beta alanine gave me better results.

Blood vessels can dilate as needed unless they are calcified. If calcified, then even arginine, citrulline, ornithine, and others won't help. If keeping the blood vessels flexible is your main goal then magnesium and vitamin K2 would be much better. However, the overall goal should be to increase metabolism which will take care of things as needed.

 

[Theo]

On that note..is Vitamin K from grasses ..ie. Wheat grass , barley grass etc.. Is that vitamin k2 ?

I take magnesium glycinate and lots of wheat grass (k2 ? )..so hopefully that should keep the pipes flexible.

 

[haidut]

On that note..is Vitamin K from grasses ..ie. Wheat grass , barley grass etc.. Is that vitamin k2 ?

I take magnesium glycinate and lots of wheat grass (k2 ? )..so hopefully that should keep the pipes flexible.

Vitamin from plants is phytonadione and is K1. It is mostly for blood coagulation. K2 (MK-4) is what you need and it can be bought online.

 

[Theo]

Thank you haidut,

So K 2 can be Mk 7 Or Mk 4....as per your suggestion I will get some Mk 4 ......it seems like even 5 mg of Mk 4 is enough per day.

Oups...it's illegal to sell K2 supplements in Canada that have more than 120mcg mk 4. Per cap..I'll have to shop around or be content with Mk 7 I suppose.

 

[Theo]

I found this info about Vit K Mk 4 to mk10.

http://wholehealthsource.blogspot.ca/20 ... 4.html?m=1

 

[Vinero]

I am going to try out lysine out of curiousity of its anti NO effects. What is the best form to take? Will the L-lysine Hydrochloride form work well?

 

[Theo]

It should say free form l lysine . personally I have used the hcl form and gotten satisfactory results. I currently have 3 bottles each a slightly different product , all hcl , all good. My favorite is the ajipure l lysine. It does have, as other ingredients, mag stearate, cellulose from the veg capsule, rice flour and silica. It's pharmaceutical grade l-lysine hcl manufactured by Aijimoto, the leading supplier of aminos for medical use.


http://www.ajiaminoscience.com/products ... e-HCl.aspx

 

[Peata]

I'm taking monohydrochloride form, just a store brand. It has about the same fillers as Theo's.

 

[uuy8778yyi]

does lysine also deplete arginine, which depletes Nitric Oxide ?

 

[Nicholas]

i got into a really bad patch and negative cycle and it was like i could not meet the demands of my environment with food anymore, so i broke down and tried Lysine. have used it for the past 3 days. each time i take it i have noticed my nasal passages clear very completely - have not had popping joints....and there is definitely more of a calm - like i don't feel burdened by dwelling on some things like i usually do. also noticed that i can digest things better. The results it has given me are all things i have gained in the past through food balancing alone....but i guess it's a good tool to use when you find it hard to meet the demands of your life.

 

[Nicholas]

does lysine also deplete arginine, which depletes Nitric Oxide ?

bump

 

[narouz]

does lysine also deplete arginine, which depletes Nitric Oxide ?

bump

This is an interesting question.
Lysine has long been a go-to supplement for those with herpes.
I have wondered whether taking lysine works in that application
specifically by depleting arginine.
Arginine has been implicated as the bad guy in triggering herpes for a long time,
so people with herpes avoid foods high in arginine.
Lysine has long been recommended to help avoid or ameliorate herpes,
but I don't think I've ever read that the mechanism by which lysine works
is lysine depletion.
haidut brought this general mechanism of "depletion" to my attention with his various threads over the years.
I don't think I understand it well enough to venture an opinion.

 

[Nicholas]

vitamin B6 seems to facilitate Lysine so perhaps B6 is a safer supplement option...

 

[kineticz]

Thought I would log in and add that lysine has been shown to modulate P5P, vitamin B6


Vitamin B6 is crucial to the transulfuration pathway in liver methylation, hence produces taurine and glutathione.


When Ray says the dangers of 'overmethylation' he should make it clear that he is referring to only one half of the methylation cycle (side which uses B12 and folate).


For mitochondrial health, the other half of methylation cycle is crucial for creatine, carnitine, glutathione.

This half requires B6, choline, glycine, methionine, ATP, magnesium, zinc.

Bye for now folks

 

[Giraffe]

post 100017 When Ray says the dangers of 'overmethylation' he should make it clear that he is referring to only one half of the methylation cycle (side which uses B12 and folate).

Can you elaborate, please?