Travis
Member
- Joined
- Jul 14, 2016
- Messages
- 3,189
We all have aluminum in our brains, introduced through diet. The best we can all do is eat a low‐aluminum diet with lots of fruit (citric acid) and a regular sleep cycle. This is a good article:
Lulu Xie had discovered increased brain perfusion levels during sleep as the brain's interstices relax and widen. Basically during sleep the cerebospinal fluid bathes the brain, dilutes metabolites, and is then ejected right before awakening (probably the very moment thee raphe nuclei starts firing, releasing vasoconstrictive serotonin). We are all left with, after sleep, a brain having a 'reset' molecular profile. During this time, melatonin is also present in the brain which can actually chelate aluminum:
I've read two experimental studies on just that, and it does chelate aluminum in vitro. Here is the hypothetical coordination complex:
click to embiggen
And, of course, the well‐known citric acid complex suggests itself:
click to embiggen
Aluminum always has a 3+ charge in solution, matched perfectly by the sum negative charges of citric acid's three carboxyl groups. Citric acid is found in fruit, is derived from glucose, and is then metabolized through its eponymous cycle. I honestly had no idea that it was 'frowned upon on this forum,' which can't be all that accurate since most people here seem unconcerned about it.
Xie, Lulu. "Sleep drives metabolite clearance from the adult brain." science (2013)
Lulu Xie had discovered increased brain perfusion levels during sleep as the brain's interstices relax and widen. Basically during sleep the cerebospinal fluid bathes the brain, dilutes metabolites, and is then ejected right before awakening (probably the very moment thee raphe nuclei starts firing, releasing vasoconstrictive serotonin). We are all left with, after sleep, a brain having a 'reset' molecular profile. During this time, melatonin is also present in the brain which can actually chelate aluminum:
Romero, Alejandro. "A review of metal‐catalyzed molecular damage: protection by melatonin." Journal of pineal research (2014)
I've read two experimental studies on just that, and it does chelate aluminum in vitro. Here is the hypothetical coordination complex:
click to embiggen
And, of course, the well‐known citric acid complex suggests itself:
click to embiggen
Aluminum always has a 3+ charge in solution, matched perfectly by the sum negative charges of citric acid's three carboxyl groups. Citric acid is found in fruit, is derived from glucose, and is then metabolized through its eponymous cycle. I honestly had no idea that it was 'frowned upon on this forum,' which can't be all that accurate since most people here seem unconcerned about it.
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