I take E only a few times per week and it seems to work fine that way for me.Thank you. After five days of taking two per day, I'm just taking one per day now. I am interested in your idea from a while back where you said something like Vitamin E is stored in the liver and can last 48+ hours, so a person might be able to take it a few times per week instead of daily. For now I am taking it daily but at some point I would like to try spacing out the dose.