Velve921
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- Joined
- Aug 7, 2014
- Messages
- 1,317
Has anyone ever taken succinic acid? Particularly for mercury detox? If so what is a good supplement?
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A complete list of protective nutritional chemicals and natural drugs or analogs to our endogenous protective factors would be very long, but we should give special thought to certain ones, including succinic acid, which stimulates respiration and protective steroid synthesis
Filatov found that stressed tissues of both plants and animals produce protective and stimulating substances, which can be extracted for medical use. He identified succinic acid as a component of his extracts. Szent-Gyorgyi found that succinic acid stimulates respiration, which might explain why it promotes synthesis of pregnenolone and related steroids. It and fumaric acid are now considered to be adaptogens. Since succinic acid safely chelates toxic heavy metals out of mitochondria, it might also safely carry copper into the mitochondria. Succinic acid is also closely associated with GABA metabolism (gamma-amino butyric acid is converted to succinic semialdehyde in a transamination reaction), and so is probably complementary to the GABA analogs GHB (gamma-hydroxy butyrate) and its lactone (which has anti-viral activity). GABA analogs are now one of the most actively studied classes of adaptogens. GABA has a wide range of stress-blocking actions, including neural inhibition, progesterone promotion, and blood sugar regulation.
Ewlevy1 said:Bradley,
What results did you have?
Maybe this is why alpha tocopherol succinate showed greater anti-cancer properties than the rest of the forms of vitamin E used.
IIRC a few decades ago, the bulk manufacturer (by ADM etc.) of tocopherols changed to the acetate form from the succinate form, for a very minor cost savings. It may be an urban rumor, but the industrial savings was said to be a few pennies per ton. It may account for the less impressive recent responses to boosting vitamin E.
I have wondered if the Shutes in their dramatic findings used essentially the succinate form of vitamin E, but I do not recall it specified in many of their writings.
DoctorYourself.com - Cancer Treatment with Vitamins
“Vitamin E (d alpha tocopherol succinate). This water soluble form has the greatest efficacy in controlling cancer cell growth in the test tube and is the one I recommend should be used. The dose ranges from 400 to 1200 International Units daily. Vitamin E is the major fat soluble anti- oxidant in the body and plays a role by decreasing the concentration of free radicals which are thought to be involved in the creation of the cancer. It also decreases the risk of heart disease, thus confirming what was found over fifty years in Ontario by Drs. Wilfrid and Evan Shute.”
The vast majority of manufacturers use pure d-alpha tocopherol, dl-alpha tocopherol or mixed tocopherols. Mixed tocopherols and tocopherol acetate are second to them and tocopherol succinate is the last. Only Now Foods and PureBulk have it in decent quantities.
Yeah, that quote it's from Abraham Hoffer. He was familiar with the shutte work. Some say they used a vitamin E similar to tocovit, some say it was alpha-tocopherol succinate.
Yes, the vitamin "manufacturers" use source material from other businesses whose production is not especially transparent. Without start-of-the-art assaying combined with time travel, it is difficult to compare nutrient quality across generations.
Hoffer lived into his 90's and was an active practitioner through late age, a good demonstration of supportive nutrition.
IIRC a few decades ago, the bulk manufacturer (by ADM etc.) of tocopherols changed to the acetate form from the succinate form, for a very minor cost savings. It may be an urban rumor, but the industrial savings was said to be a few pennies per ton. It may account for the less impressive recent responses to boosting vitamin E.
I have wondered if the Shutes in their dramatic findings used essentially the succinate form of vitamin E, but I do not recall it specified in many of their writings.
DoctorYourself.com - Cancer Treatment with Vitamins
“Vitamin E (d alpha tocopherol succinate). This water soluble form has the greatest efficacy in controlling cancer cell growth in the test tube and is the one I recommend should be used. The dose ranges from 400 to 1200 International Units daily. Vitamin E is the major fat soluble anti- oxidant in the body and plays a role by decreasing the concentration of free radicals which are thought to be involved in the creation of the cancer. It also decreases the risk of heart disease, thus confirming what was found over fifty years in Ontario by Drs. Wilfrid and Evan Shute.”
So I have been taking succinic acid for a couple of days now... not much actualy (as per haidut's reccomendation 200-250 mg twice a day) and the only benefit I can see for now is it increases libido like no other supplement I have ever taken before (includincg zinc, taurine, prohormones...). Anybody else experienced this effect? Even after nights of very poor sleep (frequent sleep interuption because 2 toddlers infected with chickenpox) all I can think about is sex. In the past when my sleep was lousy my libido would be rather weak.