- Joined
- Jul 29, 2023
- Messages
- 242
I decided to go over all of the organic acids tests (OAT) I've run in the past on my clients to see if I could find correlations between 5-HIAA and poorer health status at the time of sample collection, and low and behold I saw this:
5-HIAA, the serotonin metabolite is more than 3x higher than the top of the reference range, and along with it quinolinic acid is elevated indicating a lot of inflammation. But that's just the start of it...
This person had recently been in hospital for a couple of weeks with severe health issues, and a bunch of other markers were indicating a lot of dysfunction.
For example, signs of severe mitochondrial dysfunction (basically only one marker within range, rest is very elevated):
Also build up of lactic and pyruvic acid:
A lot of Candida and yeast overgrowth:
More indicators of intestinal dysbiosis (likely due to colonisation after the antibiotics):
Strong indication of glutathione deficiency (marker is even more elevated when factoring in creatinine and sample dilution):
And a riboflavin deficiency to boot:
This is pretty much the only time I've seen such an elevated 5-HIAA, and just so happens to be in the person with the most health issues we've ever ran the test on. Pretty fascinating. I wonder could the serotonin be a response to all these stressors or a driver of dysfunction. It may indeed be a combination of the two, but it certainly merits further research.
5-HIAA, the serotonin metabolite is more than 3x higher than the top of the reference range, and along with it quinolinic acid is elevated indicating a lot of inflammation. But that's just the start of it...
This person had recently been in hospital for a couple of weeks with severe health issues, and a bunch of other markers were indicating a lot of dysfunction.
For example, signs of severe mitochondrial dysfunction (basically only one marker within range, rest is very elevated):
Also build up of lactic and pyruvic acid:
A lot of Candida and yeast overgrowth:
More indicators of intestinal dysbiosis (likely due to colonisation after the antibiotics):
Strong indication of glutathione deficiency (marker is even more elevated when factoring in creatinine and sample dilution):
And a riboflavin deficiency to boot:
This is pretty much the only time I've seen such an elevated 5-HIAA, and just so happens to be in the person with the most health issues we've ever ran the test on. Pretty fascinating. I wonder could the serotonin be a response to all these stressors or a driver of dysfunction. It may indeed be a combination of the two, but it certainly merits further research.
