From KMUD radio program: Serotonin, endotoxin, stressSuch_Saturation said:But an appendix must explode for a reason, things don't just explode out of nowhere.
Ray said
(serotonin) It's a defensive chemical everywhere. It's one of the primitive protective factors, for example in the bowel it causes spasms that clean out the bowel. When you eat something poisonous it causes diarrhea and that's protective, but if the process keeps up too long, it increases serotonin, 95% of it being produced in the bowels, and only 3,4,5% in the organs, such as the brain, and if the irritation of the bowel keeps up very long, the circulation in the bloodstream becomes a problem systemically and it will cause vascular spasms, vascular leakiness, inflammation, for example when you have prolonged irritation to the intestines, tumors begin to promote serotonin release, starting mainly in the appendix.