I'm doing theoretical investigating for my 12 year old son. He is very muscular and lean. He turned 12 this past April and within the last 2 months has developed a lump under his right nipple.
I understand this is quite common in pubescent boys, but I also understand that if it doesn't go away, treatments become much less successful and are limited to surgery.
The lump is relatively large...about the size of a small bean.
I'm very comfortable experimenting with relatively risky compounds on myself, but not my son, especially hormonal.
With that being said, for years I've been fond of the idea of topical tamoxifen/nolvadex and applying a small amount only on that nipple. My concern would be any systemic effects throughout his body, but my logic is that this would be far less than oral administration.
I'm able to get Tamoxifen Citrate by the gram.
This article below indicates that: "When tamoxifen is taken by mouth, it goes through the gut and into the liver, where it’s broken down into two main active forms, 4-OHT and endoxifen. If we put any drug on the skin that goes directly into the breast, it has to be an active form like 4-OHT, because it won’t pass through the liver to be activated..
So this worries me that tamoxifen's metabolites are what actually "do the work" and so, topical application of tamoxifen may be pointless.
I'm curious on everyone's thoughts on this.
Any ideas on dosing?
Any other less risky ideas for a 12 year old boy?
I understand this is quite common in pubescent boys, but I also understand that if it doesn't go away, treatments become much less successful and are limited to surgery.
The lump is relatively large...about the size of a small bean.
I'm very comfortable experimenting with relatively risky compounds on myself, but not my son, especially hormonal.
With that being said, for years I've been fond of the idea of topical tamoxifen/nolvadex and applying a small amount only on that nipple. My concern would be any systemic effects throughout his body, but my logic is that this would be far less than oral administration.
I'm able to get Tamoxifen Citrate by the gram.
This article below indicates that: "When tamoxifen is taken by mouth, it goes through the gut and into the liver, where it’s broken down into two main active forms, 4-OHT and endoxifen. If we put any drug on the skin that goes directly into the breast, it has to be an active form like 4-OHT, because it won’t pass through the liver to be activated..
So this worries me that tamoxifen's metabolites are what actually "do the work" and so, topical application of tamoxifen may be pointless.
Getting Under Your Skin with Tamoxifen Gel
In a gel applied directly to the breasts, the anti-estrogen drug tamoxifen may help prevent cancer and fight DCIS — with few side effects.
www.curetoday.com
I'm curious on everyone's thoughts on this.
Any ideas on dosing?
Any other less risky ideas for a 12 year old boy?