This is a deadly compound since its effective dose is just slightly less than the lowest reported deadly dose.
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This is a deadly compound since its effective dose is just slightly less than the lowest reported deadly dose.
FYI, the lowest reported deadly dose (7mg/kg) seems to have been reported only once, in the 1930s, even though it was commonly used at the time. Apart from that one report, the reported lethal dose is no less than 5 times the effective dose, which is similar to aspirin.Charlie said:This is a deadly compound since its effective dose is just slightly less than the lowest reported deadly dose.
http://tnation.t-nation.com/free_online ... itrophenol
Only once is enough. I personally don't think being thin is worth losing my life over. I've been ultra thin a few times and it's not all it's cracked up to be. Just seems quite extreme and dangerous. In our society obsessed with thinness to the point of people mutilating their bodies with bariatric surgery people will literally do anything to look like airbrushed celebrities. That's what I find so refreshing about Peat's work, it's about sensible approaches to health not jeopardizing health to achieve some phony ideal body shape or size.visionofstrength said:FYI, the lowest reported deadly dose (7mg/kg) seems to have been reported only once, in the 1930s, even though it was commonly used at the time. Apart from that one report, the reported lethal dose is no less than 5 times the effective dose, which is similar to aspirin.Charlie said:This is a deadly compound since its effective dose is just slightly less than the lowest reported deadly dose.
http://tnation.t-nation.com/free_online ... itrophenol
Hey Blossom, I don't want to get threadjacked here. But this thread is not about DNP, except as an illustration of how uncoupling works.*Blossom said:Only once is enough. I personally don't think being thin is worth losing my life over. I've been ultra thin a few times and it's not all it's cracked up to be. Just seems quite extreme and dangerous. In our society obsessed with thinness to the point of people mutilating their bodies with bariatric surgery people will literally do anything to look like airbrushed celebrities. That's what I find so refreshing about Peat's work, it's about sensible approaches to health not jeopardizing health to achieve some phony ideal body shape or size.visionofstrength said:FYI, the lowest reported deadly dose (7mg/kg) seems to have been reported only once, in the 1930s, even though it was commonly used at the time. Apart from that one report, the reported lethal dose is no less than 5 times the effective dose, which is similar to aspirin.Charlie said:This is a deadly compound since its effective dose is just slightly less than the lowest reported deadly dose.
http://tnation.t-nation.com/free_online ... itrophenol
Thread Jack wasn't my intention VoS.visionofstrength said:Hey Blossom, I don't want to get threadjacked here. But this thread is not about DNP, except as an illustration of how uncoupling works.*Blossom said:Only once is enough. I personally don't think being thin is worth losing my life over. I've been ultra thin a few times and it's not all it's cracked up to be. Just seems quite extreme and dangerous. In our society obsessed with thinness to the point of people mutilating their bodies with bariatric surgery people will literally do anything to look like airbrushed celebrities. That's what I find so refreshing about Peat's work, it's about sensible approaches to health not jeopardizing health to achieve some phony ideal body shape or size.visionofstrength said:FYI, the lowest reported deadly dose (7mg/kg) seems to have been reported only once, in the 1930s, even though it was commonly used at the time. Apart from that one report, the reported lethal dose is no less than 5 times the effective dose, which is similar to aspirin.Charlie said:This is a deadly compound since its effective dose is just slightly less than the lowest reported deadly dose.
http://tnation.t-nation.com/free_online ... itrophenol
This thread is about having a high metabolic rate, and being thin naturally, really without trying, while you eat everything you want! That is what happens, amazingly, with Peat's many "uncouplers".
And that really is all it's cracked up to be, I can tell you from personal experience!
*Peat actually mentions DNP, not unfavorably.
That's a great question. I sometimes ask myself what would happen in an end-of-the-world scenario, and which would I want in my prepper's bag. I think I'd say I need them all. I can't think which ones to eliminate!taylor108 said:So, which uncoupling do you think is the most effective, or do you just try and utilize all of them? Or what is a good starting point as far as uncoupling goes?
Yes, I made a post above with my own diet, which may not work for you. I only eat what I think Peat himself eats.taylor108 said:And when you say you eat a lot and stay thin, do you mean you are still eating peat-approved foods (no pufas or grains, etc.) or anything you want?
visionofstrength said:This thread is about having a high metabolic rate, and being thin naturally, really without trying, while you eat everything you want! That is what happens, amazingly, with Peat's many "uncouplers".
I would respectfully ask if anyone on here actually does this? Has anyone here had their CO2 measured? Or gone in a metabolic chamber to see what their metabolism is?aquaman said:It's a MIRACLE!
visionofstrength said:This thread is about having a high metabolic rate, and being thin naturally, really without trying, while you eat everything you want! That is what happens, amazingly, with Peat's many "uncouplers".
If this was so amazingly, miraculously easy as you say it is, then everyone on here would be miraculously thin.
visionofstrength said:I would respectfully ask if anyone on here actually does this? Has anyone here had their CO2 measured? Or gone in a metabolic chamber to see what their metabolism is?
If you have, and you have a CO2 level of 6%, then I can assure you, you are miraculously thin!
All of this is so true, m! The challenge for me is to try to explain this in a way that people care about, when they are subjected to (what I think you could fairly call) the brainwashing of science and medicine, much of which is either blatantly false, or espoused by self-interested experts who have no real proof for their claims.Milklove said:If you know what you are doing, it is relatively easy to increase your metabolic rate. The real problems are having enough glycogen in your liver, keeping intestinal inflammation as low as possible and having an adequate supply of nutrients and energy.
The thread shouldn't really be about getting lean. All the things mentioned by VoS are powerful field stabilizers and have far ranging effects on the body, which should be helpful for a lot of degenerative diseases. If I had cancer, I would take exactly the same approach as described by VoS.
I also remember Ray saying, that if someone doesn't exercise at all, one can get the same benefits on a cellular level by temporarily uncoupling the mitochondria.
Yes, I've often thought about how to prove this, in an open source manner, by providing a replicable protocol that anyone can follow. The CO2 sensor to do it costs about $400, and you need a Windows PC.Charlie said:visionofstrength said:I would respectfully ask if anyone on here actually does this? Has anyone here had their CO2 measured? Or gone in a metabolic chamber to see what their metabolism is?
If you have, and you have a CO2 level of 6%, then I can assure you, you are miraculously thin!
Care to provide proof that you are doing this?
As I understand it, an end tidal reading of CO2 is an accurate measure of the pCO2 you would measure with an arterial blood draw (or perhaps calculate from a venous blood draw if you have blood bicarbonate and blood pH). This assumes you have good alveolar perfusion, and if you don't you are likely to know that, because your breathing will be very labored.Blossom said:Do you mean breathing 6% CO2 or having 6% CO2 levels as measured in exhaled breath or by a blood gas analysis? Thanks
visionofstrength said:I would respectfully ask if anyone on here actually does this? Has anyone here had their CO2 measured? Or gone in a metabolic chamber to see what their metabolism is?aquaman said:It's a MIRACLE!
visionofstrength said:This thread is about having a high metabolic rate, and being thin naturally, really without trying, while you eat everything you want! That is what happens, amazingly, with Peat's many "uncouplers".
If this was so amazingly, miraculously easy as you say it is, then everyone on here would be miraculously thin.
If you have, and you have a CO2 level of 6%, then I can assure you, you are miraculously thin!
visionofstrength said:What's your view of dosing uncouplers? and therapeutic windows? For example, I take one gram of aspirin on waking up, and then 325 mg roughly every two hours or so, trying to keep within the optimal plasma concentration shown here:Such_Saturation said:I did not recommend butter and aspirin. Remember aspirin blocks beta-oxidation in the first place.
http://www.ncbi.nlm.nih.gov/pmc/article ... p00344.pdf
Each of Peat's "uncouplers" or "redox balancers" may have a similar therapeutic window? And too much may not be a good thing? Users of DNP report that it, too, has a safe minimal effective dose, though I've not used it. Consider DHEA, for example. which Peat thinks should be limited to only 5mg in a dose! My milligram scale barely registers 5 mg!
But anecdotally, just a 5 mg speck of DHEA in combination with thyroid and progesterone, as Peat suggests, seems to be a potent uncoupler!
[Edit: there may be a therapeutic window for the saturated fatty acid uncouplers, like butyric acid in butter. Weston A. Price reported that teaspoon amounts of butter oil improved the health of his patients greatly. Peat advises teaspoon amounts of coconut oil.]